Key points

  • We recommend to consult your poison centre when considering the use of these chelating agents.
  • Acute exposure to heavy metals can lead to life-threatening clinical manifestations (e.g., lead encephalopathy).
  • Administration of a chelating agent within 2 hours or less may be indicated after the diagnosis of acute heavy metal poisoning is made. 
  • Heavy metals serum concentrations are available through specialized laboratories.
  • This monograph lists chelating agents and only provides information on their most common indications, routes of administration, availability, and recommended stocking levels. 
  • For any additional information, such as dosing recommendations, adverse effects, monitoring and endpoints of treatment, consult your poison centre.

Last updated : 2022-06-23