Key points  

  • We recommend to consult your poison centre with the use of this antidote.
  • It is important to administer pyridoxine without waiting for clinical signs of isoniazid poisoning.
  • Benzodiazepines should be used together with pyridoxine for treating convulsions associated with isoniazid, hydrazine, and gyromitra poisoning; combinig these treatments provides a synergistic effect.

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Last updated: 28-05-2018